Recombinant Human ANKS1B Protein, MYC/DDK-tagged

• Cat.No.: ANKS1B-2164H
• Product Overview: Recombinant human ANKS1B protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 46.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B [ Homo sapiens ]
• Official Symbol: ANKS1B
• Synonyms: AIDA; AIDA-1; ANKS2; cajalin-2; EB-1; EB1
• Gene ID: 56899
• mRNA Refseq: NM_001204065
• Protein Refseq: NP_001190994
• MIM: 607815
• UniProt ID: Q7Z6G8