Recombinant Human AQP1, GST-tagged

• Cat.No.: AQP1-9779H
• Product Overview: Recombinant Human AQP1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-50a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: AQP1 aquaporin 1 (Colton blood group) [ Homo sapiens ]
• Official Symbol: AQP1
• Synonyms: AQP1; aquaporin 1 (Colton blood group); aquaporin 1 (channel forming integral protein, 28kDa) , aquaporin 1 (channel forming integral protein, 28kDa, CO blood group) , CO, Colton blood group; aquaporin-1; CHIP28; aquaporin-CHIP; Colton blood group; urine water channel; channel-like integral membrane protein, 28-kDa; water channel protein for red blood cells and kidney proximal tubule; aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); CO; AQP-CHIP; MGC26324
• Gene ID: 358
• mRNA Refseq: NM_001185060
• Protein Refseq: NP_001171989
• MIM: 107776
• UniProt ID: P29972
• Chromosome Location: 7p14
• Pathway: Aquaporin-mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Passive Transport by Aquaporins, organism-specific biosystem; Proximal tubule bicarbonate reclamation, organism-specific biosystem; Proximal tubule bicarbonate reclamation, conserved biosystem; Regulation of Water Balance by Renal Aquaporins, organism-specific biosystem
• Function: ammonia transmembrane transporter activity; carbon dioxide transmembrane transporter activity; glycerol transmembrane transporter activity; intracellular cGMP activated cation channel activity; nitric oxide transmembrane transporter activity; potassium ch