Recombinant Human ARRB2, GST-tagged
Cat.No. : | ARRB2-9893H |
Product Overview : | Recombinant Human ARRB2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 162-408a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | ARRB2 arrestin, beta 2 [ Homo sapiens ] |
Official Symbol : | ARRB2 |
Synonyms : | ARRB2; arrestin, beta 2; ARR2; beta-arrestin-2; arrestin 3; BARR2; DKFZp686L0365; arrestin beta-2; ARB2; |
Gene ID : | 409 |
mRNA Refseq : | NM_001257328 |
Protein Refseq : | NP_001244257 |
MIM : | 107941 |
UniProt ID : | P32121 |
Chromosome Location : | 17p13 |
Pathway : | ALK1 signaling events, organism-specific biosystem; Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Arf6 signaling events, organism-specific biosystem; Atypical NF-kappaB pathway, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; |
Function : | G-protein coupled receptor binding; angiotensin receptor binding; protein binding; receptor binding; ubiquitin protein ligase binding; |
Products Types
◆ Recombinant Protein | ||
ARRB2-459R | Recombinant Rat ARRB2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ARRb2-3639H | Recombinant Human ARRb2 protein(Asp262~Cys430), His-GST-tagged | +Inquiry |
ARRB2-26621TH | Recombinant Human ARRB2 | +Inquiry |
ARRB2-0340H | Recombinant Human ARRB2 Protein (Met1-Cys409), C-His-tagged | +Inquiry |
ARRB2-803R | Recombinant Rat ARRB2 Protein | +Inquiry |
◆ Lysates | ||
ARRB2-130HCL | Recombinant Human ARRB2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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