Recombinant Human ATL1, GST-tagged
Cat.No. : | ATL1-9984H |
Product Overview : | Recombinant Human ATL1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | N-term-350a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | ATL1 atlastin GTPase 1 [ Homo sapiens ] |
Official Symbol : | ATL1 |
Synonyms : | ATL1; atlastin GTPase 1; spastic paraplegia 3A (autosomal dominant) , SPG3, SPG3A; atlastin-1; AD FSP; atlastin; FSP1; GBP-3; hGBP3; GTP-binding protein 3; guanylate-binding protein 3; spastic paraplegia 3 protein A; brain-specific GTP-binding protein; guanine nucleotide-binding protein 3; GBP3; SPG3; HSN1D; SPG3A; AD-FSP; atlastin1; |
Gene ID : | 51062 |
mRNA Refseq : | NM_001127713 |
Protein Refseq : | NP_001121185 |
MIM : | 606439 |
UniProt ID : | Q8WXF7 |
Chromosome Location : | 14q21.3 |
Function : | GTP binding; GTPase activity; hydrolase activity; identical protein binding; nucleotide binding; protein binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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