Recombinant Human ATP1A1, His-tagged
Cat.No. : | ATP1A1-10004H |
Product Overview : | Recombinant Human ATP1A1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 346-680a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide [ Homo sapiens ] |
Official Symbol : | ATP1A1 |
Synonyms : | ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide; sodium/potassium-transporting ATPase subunit alpha-1; sodium pump 1; Na+/K+ ATPase 1; Na,K-ATPase alpha-1 subunit; sodium pump subunit alpha-1; Na+, K+ ATPase alpha subunit; Na(+)/K(+) ATPase alpha-1 subunit; Na, K-ATPase, alpha-A catalytic polypeptide; sodium-potassium-ATPase, alpha 1 polypeptide; Na,K-ATPase catalytic subunit alpha-A protein; MGC3285; MGC51750; |
Gene ID : | 476 |
mRNA Refseq : | NM_000701 |
Protein Refseq : | NP_000692 |
MIM : | 182310 |
UniProt ID : | P05023 |
Chromosome Location : | 1p13 |
Pathway : | Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Carbohydrate digestion and absorption, organism-specific biosystem; Carbohydrate digestion and absorption, conserved biosystem; Cardiac muscle contraction, organism-specific biosystem; |
Function : | 4-nitrophenylphosphatase activity; ATP binding; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; hydrolase activity; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; meta |
Products Types
◆ Recombinant Protein | ||
ATP1A1-275R | Recombinant Rhesus Macaque ATP1A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATP1A1-461R | Recombinant Rabbit ATP1A1 Protein, His-tagged | +Inquiry |
ATP1A1-848M | Recombinant Mouse ATP1A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATP1A1-399H | Recombinant Human ATP1A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATP1A1-460H | Recombinant Human ATP1A1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ATP1A1-8613HCL | Recombinant Human ATP1A1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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