Recombinant Human ATP, His-tagged
Cat.No. : | ATP6V1D-10045H |
Product Overview : | Recombinant Human ATPHis-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c, c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 1-247a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D [ Homo sapiens ] |
Official Symbol : | ATP6V1D |
Synonyms : | ATP6V1D; ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D; ATP6M, ATPase, H+ transporting, lysosomal (vacuolar proton pump); V-type proton ATPase subunit D; VATD; VMA8; V-ATPase D subunit; V-ATPase subunit D; vacuolar H-ATPase subunit D; vacuolar proton pump D subunit; vacuolar proton pump subunit D; vacuolar ATP synthase subunit D; vacuolar proton-ATPase subunit D; V-ATPase 28 kDa accessory protein; vacuolar proton pump delta polypeptide; ATPase, H+ transporting lysosomal, member M; H(+)-transporting two-sector ATPase, subunit M; ATPase, H+ transporting, lysosomal (vacuolar proton pump); ATP6M; |
Gene ID : | 51382 |
mRNA Refseq : | NM_015994 |
Protein Refseq : | NP_057078 |
MIM : | 609398 |
UniProt ID : | Q9Y5K8 |
Chromosome Location : | 14q23-q24.2 |
Pathway : | Collecting duct acid secretion, organism-specific biosystem; Collecting duct acid secretion, conserved biosystem; Epithelial cell signaling in Helicobacter pylori infection, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, conserved biosystem; Insulin receptor recycling, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; |
Function : | ATPase activity, coupled to transmembrane movement of substances; protein binding; proton-transporting ATPase activity, rotational mechanism; |
Products Types
◆ Recombinant Protein | ||
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ATP6V1D-879M | Recombinant Mouse ATP6V1D Protein, His (Fc)-Avi-tagged | +Inquiry |
ATP6V1D-468R | Recombinant Rhesus monkey ATP6V1D Protein, His-tagged | +Inquiry |
ATP6V1D-7632Z | Recombinant Zebrafish ATP6V1D | +Inquiry |
ATP6V1D-2163M | Recombinant Mouse ATP6V1D Protein | +Inquiry |
◆ Lysates | ||
ATP6V1D-50HCL | Recombinant Human ATP6V1D lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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