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Recombinant Human BBOX1, His-tagged

Cat.No. : BBOX1-10149H
Product Overview : Recombinant Human BBOX1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
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Description : This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation.
Source : E.coli
Species : Human
Tag : His
Protein length : 1-387a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 [ Homo sapiens ]
Official Symbol : BBOX1
Synonyms : BBOX1; butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1; BBOX; gamma-butyrobetaine dioxygenase; BBH; G BBH; gamma BBH; gamma-butyrobetaine hydroxylase; gamma-butyrobetaine,2-oxoglutarate dioxygenase 1; G-BBH; gamma-BBH;
Gene ID : 8424
mRNA Refseq : NM_003986
Protein Refseq : NP_003977
MIM : 603312
UniProt ID : O75936
Chromosome Location : 11p
Pathway : Carnitine synthesis, organism-specific biosystem; L-carnitine biosynthesis, organism-specific biosystem; Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem;
Function : gamma-butyrobetaine dioxygenase activity; gamma-butyrobetaine dioxygenase activity; gamma-butyrobetaine dioxygenase activity; iron ion binding; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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