Recombinant Human BBOX1, His-tagged BBOX1-10149H

Recombinant Human BBOX1, His-tagged


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Recombinant Human BBOX1, His-tagged

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Cat.No. : BBOX1-10149H
Product Overview : Recombinant Human BBOX1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation.
Source : E.coli
Species : Human
Tag : His
Protein length : 1-387a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 [ Homo sapiens ]
Official Symbol : BBOX1
Synonyms : BBOX1; butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1; BBOX; gamma-butyrobetaine dioxygenase; BBH; G BBH; gamma BBH; gamma-butyrobetaine hydroxylase; gamma-butyrobetaine,2-oxoglutarate dioxygenase 1; G-BBH; gamma-BBH;
Gene ID : 8424
mRNA Refseq : NM_003986
Protein Refseq : NP_003977
MIM : 603312
UniProt ID : O75936
Chromosome Location : 11p
Pathway : Carnitine synthesis, organism-specific biosystem; L-carnitine biosynthesis, organism-specific biosystem; Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem;
Function : gamma-butyrobetaine dioxygenase activity; gamma-butyrobetaine dioxygenase activity; gamma-butyrobetaine dioxygenase activity; iron ion binding; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation

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