"BIGH3" Related Products

Recombinant Human BIGH3, GST-tagged

Cat.No.: BIGH3-10227H
Product Overview: Recombinant Human BIGH3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
Source: E.coli
Species: Human
Tag: GST
Protein length: 199-406a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: TGFBI transforming growth factor, beta-induced, 68kDa [ Homo sapiens ]
Official Symbol: TGFBI
Synonyms: TGFBI; transforming growth factor, beta-induced, 68kDa; CSD1, CSD2, CSD3, LCD1, transforming growth factor, beta induced, 68kD; transforming growth factor-beta-induced protein ig-h3; BIGH3; CDB1; CDGG1; RGD-CAP; beta ig-h3; kerato-epithelin; RGD-containing collagen-associated protein; CSD; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1;
Gene ID: 7045
mRNA Refseq: NM_000358
Protein Refseq: NP_000349
MIM: 601692
UniProt ID: Q15582
Chromosome Location: 5q31
Pathway: Amyloids, organism-specific biosystem; Disease, organism-specific biosystem;
Function: extracellular matrix binding; integrin binding;

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