Recombinant Human BIGH3, GST-tagged

• Cat.No.: BIGH3-10227H
• Product Overview: Recombinant Human BIGH3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 199-406a.a.
• Description: This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: TGFBI transforming growth factor, beta-induced, 68kDa [ Homo sapiens ]
• Official Symbol: TGFBI
• Synonyms: TGFBI; transforming growth factor, beta-induced, 68kDa; CSD1, CSD2, CSD3, LCD1, transforming growth factor, beta induced, 68kD; transforming growth factor-beta-induced protein ig-h3; BIGH3; CDB1; CDGG1; RGD-CAP; beta ig-h3; kerato-epithelin; RGD-containing collagen-associated protein; CSD; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1
• Gene ID: 7045
• mRNA Refseq: NM_000358
• Protein Refseq: NP_000349
• MIM: 601692
• UniProt ID: Q15582
• Chromosome Location: 5q31
• Pathway: Amyloids, organism-specific biosystem; Disease, organism-specific biosystem
• Function: extracellular matrix binding; integrin binding