Recombinant Human BIGH3, GST-tagged
| Cat.No. : | BIGH3-10227H |
| Product Overview : | Recombinant Human BIGH3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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- Gene Information
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| Description : | This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. |
| Source : | E.coli |
| Species : | Human |
| Tag : | GST |
| Protein length : | 199-406a.a. |
| Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
| Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
| Gene Name : | TGFBI transforming growth factor, beta-induced, 68kDa [ Homo sapiens ] |
| Official Symbol : | TGFBI |
| Synonyms : | TGFBI; transforming growth factor, beta-induced, 68kDa; CSD1, CSD2, CSD3, LCD1, transforming growth factor, beta induced, 68kD; transforming growth factor-beta-induced protein ig-h3; BIGH3; CDB1; CDGG1; RGD-CAP; beta ig-h3; kerato-epithelin; RGD-containing collagen-associated protein; CSD; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; |
| Gene ID : | 7045 |
| mRNA Refseq : | NM_000358 |
| Protein Refseq : | NP_000349 |
| MIM : | 601692 |
| UniProt ID : | Q15582 |
| Chromosome Location : | 5q31 |
| Pathway : | Amyloids, organism-specific biosystem; Disease, organism-specific biosystem; |
| Function : | extracellular matrix binding; integrin binding; |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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