Recombinant Human BRIP1, His-tagged
Cat.No. : | BRIP1-10291H |
Product Overview : | Recombinant Human BRIP1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 1-342a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | BRIP1 BRCA1 interacting protein C-terminal helicase 1 [ Homo sapiens ] |
Official Symbol : | BRIP1 |
Synonyms : | BRIP1; BRCA1 interacting protein C-terminal helicase 1; Fanconi anemia group J protein; BACH1; BRCA1/BRCA2 associated helicase 1; FANCJ; OF; ATP-dependent RNA helicase BRIP1; BRCA1/BRCA2-associated helicase 1; BRCA1-associated C-terminal helicase 1; BRCA1-binding helicase-like protein BACH1; FLJ90232; MGC126521; MGC126523; |
Gene ID : | 83990 |
mRNA Refseq : | NM_032043 |
Protein Refseq : | NP_114432 |
MIM : | 605882 |
UniProt ID : | Q9BX63 |
Chromosome Location : | 17q22.2 |
Pathway : | DNA Repair, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Homologous DNA pairing and strand exchange, organism-specific biosystem; Homologous Recombination Repair, organism-specific biosystem; Homologous recombination repair of replication-independent double-strand breaks, organism-specific biosystem; |
Function : | ATP binding; ATP-dependent DNA helicase activity; DNA binding; helicase activity; hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; nucleotide binding; protein binding; |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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