Recombinant Human BRIP1 HEK293T cell lysate

• Cat.No.: BRIP1-10HL
• Product Overview: Human BRIP1 derived in Human HEK293T cell line.

Specification

• Description: The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations.
• Source: Human HEK293T cell line
• Species: Human
• Tag: C-terminal Myc/DDK
• Form: 1 vial of 100 µg gene specific transient over-expression cell lysate in RIPA buffer
  1 vial of 100 µg empty vector transfected control cell lysate in RIPA buffer
  1 vial of 250ul 2xSDS Sample Buffer (4% SDS, 125mM Tris-HCl pH6.8, 10% Glycerol, 0.002% Bromph
• Molecular Mass: 140.7 kDa
• Storage: Upon receiving, store the sample at -20 centigrade. Lysate samples are stable for 12 months from date of receipt when stored at -20 centigrade. Avoid repeated freeze-thaw cycles.
  Lysate samples can be diluted with 2xSDS Sample Buffer provided. After dilution, the protein sample should be aliquoted and stored at -20 centigrade for long term storage. Prior to SDS-PAGE fractionation, boil the lysate for 5 minutes.
• Shipping: The lysate is shipped with dry ice

Gene Information

• Gene Name: BRIP1 BRCA1 interacting protein C-terminal helicase 1 [ Homo sapiens ]
• Official Symbol: BRIP1
• Synonyms: BRIP1; BRCA1 interacting protein C-terminal helicase 1; Fanconi anemia group J protein; BACH1; BRCA1/BRCA2 associated helicase 1; FANCJ; OF; ATP-dependent RNA helicase BRIP1; BRCA1/BRCA2-associated helicase 1; BRCA1-associated C-terminal helicase 1; BRCA1-binding helicase-like protein BACH1; FLJ90232; MGC126521; MGC126523
• Gene ID: 83990
• mRNA Refseq: NM_032043
• Protein Refseq: NP_114432
• MIM: 605882
• UniProt ID: Q9BX63
• Chromosome Location: 17q22.2
• Pathway: DNA Repair, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Homologous DNA pairing and strand exchange, organism-specific biosystem; Homologous Recombination Repair, organism-specific biosystem; Homologous recombination repair of replication-independent double-strand breaks, organism-specific biosystem
• Function: ATP binding; ATP-dependent DNA helicase activity; DNA binding; helicase activity; hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; nucleotide binding; protein binding