Recombinant Human CACNA1G, His-tagged

• Cat.No.: CACNA1G-10634H
• Product Overview: Recombinant Human CACNA1G protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 396-742a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit [ Homo sapiens ]
• Official Symbol: CACNA1G
• Synonyms: calcium channel voltage dependent alpha 1G subunit; calcium channel voltage dependent T type alpha 1G subunit; calcium channel voltage dependent T type alpha1G subunit; CaV T1; Cav3 1; cav3 1c; KIAA1123; MGC117234; NBR13; voltage dependent calcium channel alpha 1G subunit isoform 11; voltage dependent T type calcium channel subunit alpha 1G; Voltage gated calcium channel subunit alpha Cav3 1; CACNA1G
• Gene ID: 8913
• mRNA Refseq: NM_018896.4
• Protein Refseq: NP_061496.2
• MIM: 604065
• UniProt ID: O43497
• Chromosome Location: 17q22
• Pathway: Axon guidance, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Developmental Biology, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; NCAM signaling for neurite out-growth, organism-specific biosystem
• Function: low voltage-gated calcium channel activity; scaffold protein binding