Recombinant Human CATSPER1, GST-tagged CATSPER1-10746H

Recombinant Human CATSPER1, GST-tagged

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Recombinant Human CATSPER1, GST-tagged

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Cat.No. : CATSPER1-10746H
Product Overview : Recombinant Human CATSPER1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. Alternatively spliced transcript variants have been found for this gene.
Source : E.coli
Species : Human
Tag : GST
Protein length : N-term-302a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : CATSPER1 cation channel, sperm associated 1 [ Homo sapiens ]
Official Symbol : CATSPER1
Synonyms : CATSPER1; cation channel, sperm associated 1; cation channel sperm-associated protein 1; CATSPER; hCatSper; sperm ion channel; sperm-associated cation channel 1; SPGF7; MGC33335; MGC33368;
Gene ID : 117144
mRNA Refseq : NM_053054
Protein Refseq : NP_444282
MIM : 606389
UniProt ID : Q8NEC5
Chromosome Location : 11q12.1
Function : protein binding; voltage-gated calcium channel activity; voltage-gated ion channel activity;

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