Recombinant Human CBLB, His-tagged

• Cat.No.: CBLB-10756H
• Product Overview: Recombinant Human CBLB protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: His
• Protein length: N-term-352a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CBLB Cbl proto-oncogene, E3 ubiquitin protein ligase B [ Homo sapiens ]
• Official Symbol: CBLB
• Synonyms: CBLB; Cbl proto-oncogene, E3 ubiquitin protein ligase B; Cas Br M (murine) ecotropic retroviral transforming sequence b , Cas Br M (murine) ectropic retroviral transforming sequence b; E3 ubiquitin-protein ligase CBL-B; Cbl b; RNF56; RING finger protein 56; SH3-binding protein CBL-B; signal transduction protein CBL-B; casitas B-lineage lymphoma proto-oncogene b; Cas-Br-M (murine) ectropic retroviral transforming sequence b; Cas-Br-M (murine) ecotropic retroviral transforming sequence b; Cbl-b; Nbla00127; FLJ36865; FLJ41152; DKFZp779A0729; DKFZp779F1443; DKFZp686J10223
• Gene ID: 868
• mRNA Refseq: NM_170662
• Protein Refseq: NP_733762
• MIM: 604491
• UniProt ID: Q13191
• Chromosome Location: 3q
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen Activates B Cell Receptor Leading to Generation of Second Messengers, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem
• Function: calcium ion binding; ligase activity; phosphotyrosine binding; protein binding; protein kinase binding; signal transducer activity; ubiquitin-protein ligase activity; zinc ion binding