Recombinant Human CCDC22, GST-tagged

• Cat.No.: CCDC22-10795H
• Product Overview: Recombinant Human CCDC22 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-350a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CCDC22 coiled-coil domain containing 22 [ Homo sapiens ]
• Official Symbol: CCDC22
• Synonyms: CCDC22; coiled-coil domain containing 22; chromosome X open reading frame 37 , CXorf37; coiled-coil domain-containing protein 22; JM1; CXorf37
• Gene ID: 28952
• mRNA Refseq: NM_014008
• Protein Refseq: NP_054727
• MIM: 300859
• UniProt ID: O60826
• Chromosome Location: Xp11.23
• Function: molecular_function