Recombinant Human CCDC56, GST-tagged CCDC56-10809H

Recombinant Human CCDC56, GST-tagged

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Recombinant Human CCDC56, GST-tagged

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Cat.No. : CCDC56-10809H
Product Overview : Recombinant Human CCDC56 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-106a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : COA3 cytochrome c oxidase assembly factor 3 [ Homo sapiens ]
Official Symbol : COA3
Synonyms : CCDC56; HSPC009; MITRAC12; cytochrome c oxidase assembly protein 3 homolog, mitochondrial; coiled-coil domain-containing protein 56; cytochrome C oxidase assembly factor 3 homolog, mitochondrial; mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa; COA3
Gene ID : 28958
mRNA Refseq : NM_001040431.1
Protein Refseq : NP_001035521.1
MIM : 614775
UniProt ID : Q9Y2R0
Chromosome Location : 17q21

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