Recombinant Human CCDC56, GST-tagged
Cat.No. : | CCDC56-10809H |
Product Overview : | Recombinant Human CCDC56 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-106a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | COA3 cytochrome c oxidase assembly factor 3 [ Homo sapiens ] |
Official Symbol : | COA3 |
Synonyms : | CCDC56; HSPC009; MITRAC12; cytochrome c oxidase assembly protein 3 homolog, mitochondrial; coiled-coil domain-containing protein 56; cytochrome C oxidase assembly factor 3 homolog, mitochondrial; mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa; COA3 |
Gene ID : | 28958 |
mRNA Refseq : | NM_001040431.1 |
Protein Refseq : | NP_001035521.1 |
MIM : | 614775 |
UniProt ID : | Q9Y2R0 |
Chromosome Location : | 17q21 |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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