Recombinant Human CDCA3, His-tagged CDCA3-11022H

Recombinant Human CDCA3, His-tagged

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Recombinant Human CDCA3, His-tagged

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Cat.No. : CDCA3-11022H
Product Overview : Recombinant Human CDCA3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
Source : E.coli
Species : Human
Tag : His
Protein length : 1-268a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : CDCA3 cell division cycle associated 3 [ Homo sapiens ]
Official Symbol : CDCA3
Synonyms : CDCA3; cell division cycle associated 3; GRCC8; TOME 1; trigger of mitotic entry 1;
Gene ID : 191588
MIM : 607749
UniProt ID : Q99618
Chromosome Location : 12p13.31

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