Recombinant Human CDKN2AIP, GST-tagged

• Cat.No.: CDKN2AIP-11062H
• Product Overview: Recombinant Human CDKN2AIP protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 230-579a.a.
• Description: This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CDKN2AIP CDKN2A interacting protein [ Homo sapiens ]
• Official Symbol: CDKN2AIP
• Synonyms: CDKN2AIP; CDKN2A interacting protein; CDKN2A-interacting protein; CARF; collaborates/cooperates with ARF (alternate reading frame) protein; FLJ20036; collaborator of ARF
• Gene ID: 55602
• mRNA Refseq: NM_017632
• Protein Refseq: NP_060102
• UniProt ID: Q9NXV6
• Chromosome Location: 4q35.1
• Function: double-stranded RNA binding; p53 binding; protein binding