Recombinant Human CENPL, His-tagged

• Cat.No.: CENPL-11098H
• Product Overview: Recombinant Human CENPL protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-364a.a.
• Description: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CENPL centromere protein L [ Homo sapiens ]
• Official Symbol: CENPL
• Synonyms: CENP-L; C1orf155; dJ383J4.3; RP3-383J4.1; centromere protein L; interphase centromere complex protein 33; chromosome 1 open reading frame 155; dJ383J4.3; Interphase centromere complex protein 3
• Gene ID: 91687
• mRNA Refseq: NM_033319.3
• Protein Refseq: NP_201576.1
• MIM: 611503
• UniProt ID: Q8N0S6
• Chromosome Location: 1q25.1
• Function: Cell Cycle,organism-specific biosystem;Cell Cycle,Mitotic,organism-specific biosystem;DNA Replication,organism-specific biosystem;M Phase,organism-specific biosystem;Mitotic M-M/G1 phases,organism-specific biosystem;Mitotic Prometaphase,organism-specific