Recombinant Human CHMP4C, His-tagged


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Recombinant Human CHMP4C, His-tagged

CHMP4C Related Products

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Cat.No. : CHMP4C-11188H
Product Overview : Recombinant Human CHMP4C protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Source : E.coli
Species : Human
Tag : His
Protein length : 1-233a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : CHMP4C charged multivesicular body protein 4C [ Homo sapiens ]
Official Symbol : CHMP4C
Synonyms : Charged multivesicular body protein 4c; CHM4C_HUMAN; CHMP4c; Chromatin-modifying protein 4c; hSnf7-3; hVps32-3; SNF7 homolog associated with Alix 3; SNF7-3; Vacuolar protein sorting-associated protein 32-3; Vps32-3;
Gene ID : 92421
mRNA Refseq : NM_152284.3
Protein Refseq : NP_689497.1
MIM : 610899
UniProt ID : Q96CF2
Chromosome Location : 8q21.13
Function : ESCRT-III complex, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Endosomal Sorting Complex Required For Transport (ESCRT), organism-specific biosystem; Membrane Trafficking, organism-specific bios
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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