Recombinant Human CHMP4C, His-tagged CHMP4C-11188H

Recombinant Human CHMP4C, His-tagged

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Recombinant Human CHMP4C, His-tagged

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Cat.No. : CHMP4C-11188H
Product Overview : Recombinant Human CHMP4C protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Source : E.coli
Species : Human
Tag : His
Protein length : 1-233a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : CHMP4C charged multivesicular body protein 4C [ Homo sapiens ]
Official Symbol : CHMP4C
Synonyms : Charged multivesicular body protein 4c; CHM4C_HUMAN; CHMP4c; Chromatin-modifying protein 4c; hSnf7-3; hVps32-3; SNF7 homolog associated with Alix 3; SNF7-3; Vacuolar protein sorting-associated protein 32-3; Vps32-3;
Gene ID : 92421
mRNA Refseq : NM_152284.3
Protein Refseq : NP_689497.1
MIM : 610899
UniProt ID : Q96CF2
Chromosome Location : 8q21.13
Function : ESCRT-III complex, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Endosomal Sorting Complex Required For Transport (ESCRT), organism-specific biosystem; Membrane Trafficking, organism-specific bios

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