Recombinant Human CHST15, GST-tagged

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Recombinant Human CHST15, GST-tagged

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Cat.No. : CHST15-11228H
Product Overview : Recombinant Human CHST15 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Source : E.coli
Species : Human
Tag : GST
Protein length : 103-451a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 [ Homo sapiens ]
Official Symbol : CHST15
Synonyms : CHST15; carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15; carbohydrate sulfotransferase 15; B cell RAG associated protein; BRAG; GALNAC4S 6ST; KIAA0598; N acetylgalactosamine 4 sulfate 6 O sulfotransferase; hBRAG; B-cell RAG-associated gene protein; B cell RAG associated protein (GALNAC4S-6ST); N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase; GALNAC4S-6ST; RP11-47G11.1; MGC34346; DKFZp781H1369;
Gene ID : 51363
mRNA Refseq : NM_014863
Protein Refseq : NP_055678
MIM : 608277
UniProt ID : Q7LFX5
Chromosome Location : 10q26
Pathway : B Cell Receptor Signaling Pathway, organism-specific biosystem; Glycosaminoglycan biosynthesis - chondroitin sulfate, organism-specific biosystem; Glycosaminoglycan biosynthesis - chondroitin sulfate, conserved biosystem; chondroitin sulfate biosynthesis, organism-specific biosystem; chondroitin sulfate biosynthesis, conserved biosystem; chondroitin sulfate biosynthesis (late stages), organism-specific biosystem; chondroitin sulfate biosynthesis (late stages), conserved biosystem;
Function : 3-phosphoadenosine 5-phosphosulfate binding; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; transferase activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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