Recombinant Human cIAP1, GST-tagged
| Cat.No. : | cIAP1-11240H |
| Product Overview : | Recombinant Human cIAP1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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| Description : | The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : | E.coli |
| Species : | Human |
| Tag : | GST |
| Protein length : | 1-350a.a. |
| Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
| Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
| Gene Name : | BIRC2 baculoviral IAP repeat containing 2 [ Homo sapiens ] |
| Official Symbol : | BIRC2 |
| Synonyms : | BIRC2; baculoviral IAP repeat containing 2; API1, baculoviral IAP repeat containing 2; baculoviral IAP repeat-containing protein 2; apoptosis inhibitor 1; c IAP1; cIAP1; hiap 2; MIHB; NFR2 TRAF signalling complex protein; RNF48; IAP-2; IAP homolog B; RING finger protein 48; inhibitor of apoptosis protein 2; baculoviral IAP repeat-containing 2; NFR2-TRAF signalling complex protein; TNFR2-TRAF-signaling complex protein 2; API1; HIAP2; Hiap-2; c-IAP1; |
| Gene ID : | 329 |
| mRNA Refseq : | NM_001166 |
| Protein Refseq : | NP_001157 |
| MIM : | 601712 |
| UniProt ID : | Q13490 |
| Chromosome Location : | 11q22 |
| Pathway : | Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; CD40/CD40L signaling, organism-specific biosystem; |
| Function : | metal ion binding; protein N-terminus binding; protein binding; transcription coactivator activity; ubiquitin-protein ligase activity; zinc ion binding; |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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