Recombinant Human CIRH1A, GST-tagged

• Cat.No.: CIRH1A-11253H
• Product Overview: Recombinant Human CIRH1A protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-350a.a.
• Description: This gene encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CIRH1A cirrhosis, autosomal recessive 1A (cirhin) [ Homo sapiens ]
• Official Symbol: CIRH1A
• Synonyms: CIRH1A; cirrhosis, autosomal recessive 1A (cirhin); cirhin; CIRHIN; FLJ14728; KIAA1988; NAIC; TEX292; UTP4; small subunit (SSU) processome component; homolog (yeast); testis expressed gene 292; UTP4, small subunit (SSU) processome component, homolog; FLJ17146
• Gene ID: 84916
• mRNA Refseq: NM_032830
• Protein Refseq: NP_116219
• MIM: 607456
• UniProt ID: Q969X6
• Chromosome Location: 16q22
• Pathway: Ribosome biogenesis in eukaryotes, organism-specific biosystem; Ribosome biogenesis in eukaryotes, conserved biosystem
• Function: molecular_function