Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human CLPP, GST-tagged

Cat.No. : CLPP-11343H
Product Overview : Recombinant Human CLPP protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Unit
Price
Qty
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane.
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-277a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : CLPP ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli) [ Homo sapiens ]
Official Symbol : CLPP
Synonyms : CLPP; ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli); ClpP (caseinolytic protease, ATP dependent, proteolytic subunit, E. coli) homolog , ClpP caseinolytic protease, ATP dependent, proteolytic subunit homolog (E. coli); putative ATP-dependent Clp protease proteolytic subunit, mitochondrial; ATP dependent protease ClpAP (E. coli); proteolytic subunit; human; endopeptidase Clp; ATP-dependent protease ClpAP, proteolytic subunit, human; ClpP caseinolytic peptidase ATP-dependent, proteolytic subunit; ClpP caseinolytic protease, ATP-dependent, proteolytic subunit homolog;
Gene ID : 8192
mRNA Refseq : NM_006012
Protein Refseq : NP_006003
MIM : 601119
UniProt ID : Q16740
Chromosome Location : 19
Function : ATP binding; nucleotide binding; peptidase activity; protein binding; serine-type endopeptidase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (7)

Ask a question
Are there any potential therapeutic approaches targeting CLPP? 08/06/2022

Targeting CLPP therapeutically could offer potential in diseases related to mitochondrial dysfunction and aging.

How is the activity of CLPP regulated within the cell? 08/05/2020

CLPP activity is tightly regulated to ensure balanced protein turnover in mitochondria.

In which conditions is CLPP dysregulation observed, and what are its implications? 07/01/2020

Dysregulation of CLPP is linked to various diseases, including mitochondrial disorders.

How does CLPP contribute to mitochondrial protein quality control? 12/21/2019

It helps in degrading misfolded or damaged proteins, maintaining mitochondrial function.

What role does CLPP play in mitochondrial function and health? 07/27/2018

Proper functioning of CLPP is vital for mitochondrial health and energy production.

What is the significance of CLPP in aging and longevity? 07/26/2018

CLPP levels and activity are associated with aging, influencing cellular senescence and longevity.

What is the main function of CLPP in cellular processes? 05/13/2018

CLPP plays a crucial role in mitochondrial protein degradation and quality control.

Customer Reviews (3)

Write a review
Reviews
05/03/2022

    Very high purity level.

    11/15/2019

      Worked excellently in experiments.

      08/05/2018

        Product was well packaged.

        Ask a Question for All CLPP Products

        Required fields are marked with *

        My Review for All CLPP Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends