Recombinant Human CPE, GST-tagged CPE-11515H

Recombinant Human CPE, GST-tagged

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Recombinant Human CPE, GST-tagged

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Cat.No. : CPE-11515H
Product Overview : Recombinant Human CPE protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.
Source : E.coli
Species : Human
Tag : GST
Protein length : 126-476a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : CPE carboxypeptidase E [ Homo sapiens ]
Official Symbol : CPE
Synonyms : CPE; carboxypeptidase E; carboxypeptidase H; cobalt stimulated chromaffin granule carboxypeptidase; enkephalin convertase; insulin granule associated carboxypeptidase; CPH; prohormone-processing carboxypeptidase; insulin granule-associated carboxypeptidase; cobalt-stimulated chromaffin granule carboxypeptidase;
Gene ID : 1363
mRNA Refseq : NM_001873
Protein Refseq : NP_001864
MIM : 114855
UniProt ID : P16870
Chromosome Location : 4q32.3
Pathway : Arf6 trafficking events, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Insulin Synthesis and Processing, organism-specific biosystem; Type I diabetes mellitus, organism-specific biosystem; Type I diabetes mellitus, conserved biosystem;
Function : carboxypeptidase activity; cell adhesion molecule binding; metal ion binding; metallocarboxypeptidase activity; metallopeptidase activity; neurexin family protein binding; peptidase activity; zinc ion binding;

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