Recombinant Human CRY1, His-tagged

• Cat.No.: CRY1-11596H
• Product Overview: Recombinant Human CRY1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 236-586a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CRY1 cryptochrome 1 (photolyase-like) [ Homo sapiens ]
• Official Symbol: CRY1
• Synonyms: CRY1; cryptochrome 1 (photolyase-like); PHLL1; cryptochrome-1; photolyase-like cryptochrome 1
• Gene ID: 1407
• mRNA Refseq: NM_004075
• Protein Refseq: NP_004066
• MIM: 601933
• UniProt ID: Q16526
• Chromosome Location: 12q23-q24.1
• Pathway: BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian rhythm - mammal, organism-specific biosystem; Circadian rhythm - mammal, conserved biosystem; Diurnally regulated genes with circadian orthologs, organism-specific biosystem
• Function: NOT DNA (6-4) photolyase activity; DNA binding; blue light photoreceptor activity; NOT deoxyribodipyrimidine photo-lyase activity; double-stranded DNA binding; nucleotide binding; protein binding; protein binding transcription factor activity; protein kin