Recombinant Human CTSL1, GST-tagged
Cat.No. : | CTSL1-11690H |
Product Overview : | Recombinant Human CTSL1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-333a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | CTSL1 cathepsin L1 [ Homo sapiens ] |
Official Symbol : | CTSL1 |
Synonyms : | CTSL1; cathepsin L1; cathepsin L , CTSL; FLJ31037; cathepsin L; major excreted protein; MEP; CATL; CTSL; |
Gene ID : | 1514 |
mRNA Refseq : | NM_001257971 |
Protein Refseq : | NP_001244900 |
MIM : | 116880 |
UniProt ID : | P07711 |
Chromosome Location : | 9q21.33 |
Pathway : | Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Phagosome, organism-specific biosystem; |
Function : | cysteine-type endopeptidase activity; cysteine-type endopeptidase activity; cysteine-type peptidase activity; histone binding; peptidase activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
CTSL1-1327R | Recombinant Rat CTSL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSL1-441C | Recombinant Chlorocebus Aethiops CTSG Protein (114-333 aa), His-SUMO-tagged | +Inquiry |
CTSL1-1668R | Recombinant Rat CTSL1 Protein | +Inquiry |
CTSL1-896H | Recombinant Human CTSL1 protein, His-tagged | +Inquiry |
CTSL1-26491TH | Recombinant Human CTSL1, His-tagged | +Inquiry |
◆ Native Protein | ||
CTSL1-1859H | Native Human Cathepsin L1 | +Inquiry |
CTSL1-27406TH | Native Human CTSL1 | +Inquiry |
◆ Lysates | ||
CTSL1-3022HCL | Recombinant Human CTSL1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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