Recombinant Human CUGBP1, His-tagged
Cat.No. : | CUGBP1-11699H |
Product Overview : | Recombinant Human CUGBP1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 107-479a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | CELF1 CUGBP, Elav-like family member 1 [ Homo sapiens ] |
Official Symbol : | CELF1 |
Synonyms : | CELF1; CUGBP, Elav-like family member 1; CUG triplet repeat, RNA binding protein 1 , CUG triplet repeat, RNA binding protein 1 , CUGBP1; CUGBP Elav-like family member 1; bruno like 2; BRUNOL2; CUG RNA binding protein; CUG BP; CUGBP; EDEN BP; embryo deadenylation element binding protein; hNab50; NAB50; NAPOR; nuclear polyadenylated RNA binding protein; 50 kD; CELF-1; CUG-BP1; bruno-like 2; EDEN-BP homolog; bruno-like protein 2; CUG RNA-binding protein; deadenylation factor CUG-BP; RNA-binding protein BRUNOL-2; CUG-BP- and ETR-3-like factor 1; CUG triplet repeat RNA-binding protein 1; CUG triplet repeat, RNA binding protein 1; CUG triplet repeat, RNA-binding protein 1; 50 kDa nuclear polyadenylated RNA-binding protein; nuclear polyadenylated RNA-binding protein, 50-kD; embryo deadenylation element-binding protein homolog; CUG-BP; CUGBP1; EDEN-BP; |
Gene ID : | 10658 |
mRNA Refseq : | NM_001025596 |
Protein Refseq : | NP_001020767 |
MIM : | 601074 |
UniProt ID : | Q92879 |
Chromosome Location : | 11p11 |
Pathway : | Adipogenesis, organism-specific biosystem; mRNA processing, organism-specific biosystem; |
Function : | BRE binding; RNA binding; mRNA binding; nucleotide binding; protein binding; translation repressor activity, nucleic acid binding; |
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◆ Lysates | ||
CELF1-7590HCL | Recombinant Human CELF1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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