"CUL4B" Related Products

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Recombinant Human CUL4B, His-tagged

Cat.No.: CUL4B-11705H
Product Overview: Recombinant Human CUL4B protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.
Source: E.coli
Species: Human
Tag: His
Protein length: 1-195a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: CUL4B cullin 4B [ Homo sapiens ]
Official Symbol: CUL4B
Synonyms: CUL4B; cullin 4B; cullin-4B; CUL-4B; SFM2; MRXSC; MRXHF2; MRXS15; KIAA0695; DKFZp686F1470;
Gene ID: 8450
mRNA Refseq: NM_001079872
Protein Refseq: NP_001073341
MIM: 300304
UniProt ID: Q13620
Chromosome Location: Xq23
Pathway: Cul4-DDB1-CSA complex, organism-specific biosystem; Cul4-DDB1-DDB2 complex, organism-specific biosystem; Nucleotide excision repair, organism-specific biosystem; Nucleotide excision repair, conserved biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem; Ubiquitin mediated proteolysis, conserved biosystem;
Function: protein binding; ubiquitin protein ligase binding;

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