Recombinant Human CYP4X1, His-tagged

• Cat.No.: CYP4X1-11793H
• Product Overview: Recombinant Human CYP4X1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 160-509a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1 [ Homo sapiens ]
• Official Symbol: CYP4X1
• Synonyms: CYP4X1; cytochrome P450, family 4, subfamily X, polypeptide 1; cytochrome P450 4X1; MGC40051; CYPIVX1
• Gene ID: 260293
• mRNA Refseq: NM_178033
• Protein Refseq: NP_828847
• UniProt ID: Q8N118
• Chromosome Location: 1p33
• Pathway: Serotonergic synapse, organism-specific biosystem; acetone degradation I (to methylglyoxal), organism-specific biosystem; bupropion degradation, organism-specific biosystem; melatonin degradation I, organism-specific biosystem; nicotine degradation II, organism-specific biosystem; nicotine degradation III, organism-specific biosystem; superpathway of melatonin degradation, organism-specific biosystem
• Function: aromatase activity; electron carrier activity; heme binding; metal ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen