Recombinant Human DAD1, GST-tagged
Cat.No. : | DAD1-11817H |
Product Overview : | Recombinant Human DAD1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-113a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | DAD1 defender against cell death 1 [ Homo sapiens ] |
Official Symbol : | DAD1 |
Synonyms : | DAD1; defender against cell death 1; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; oligosaccharyltransferase 2 homolog (S. cerevisiae); OST2; DAD-1; oligosaccharyltransferase 2 homolog; oligosaccharyl transferase subunit DAD1; |
Gene ID : | 1603 |
mRNA Refseq : | NM_001344 |
Protein Refseq : | NP_001335 |
MIM : | 600243 |
UniProt ID : | P61803 |
Chromosome Location : | 14q11.2 |
Pathway : | Asparagine N-linked glycosylation, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; N-Glycan biosynthesis, organism-specific biosystem; N-Glycan biosynthesis, conserved biosystem; Oligosaccharyltransferase, organism-specific biosystem; Post-translational protein modification, organism-specific biosystem; |
Function : | contributes_to dolichyl-diphosphooligosaccharide-protein glycotransferase activity; contributes_to oligosaccharyl transferase activity; transferase activity; |
Products Types
◆ Recombinant Protein | ||
DAD1-998R | Recombinant Rhesus Macaque DAD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DAD1-1427R | Recombinant Rat DAD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DAD1-2324H | Recombinant Human DAD1 Protein, GST-tagged | +Inquiry |
DAD1-1769R | Recombinant Rat DAD1 Protein | +Inquiry |
DAD1-1739C | Recombinant Chicken DAD1 | +Inquiry |
◆ Lysates | ||
DAD1-215HCL | Recombinant Human DAD1 lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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