"DBR1" Related Products


Recombinant Human DBR1, His-tagged

Cat.No.: DBR1-11847H
Product Overview: Recombinant Human DBR1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: The protein encoded by this gene is an RNA lariat debranching enzyme that hydrolyzes 2-5 prime branched phosphodiester bonds. The encoded protein specifically targets the bonds at the branch point of excised lariat intron RNA, converting them to linear molecules that are then degraded. This protein may also be involved in retroviral replication.
Source: E.coli
Species: Human
Tag: His
Protein length: 204-544a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: DBR1 debranching enzyme homolog 1 (S. cerevisiae) [ Homo sapiens ]
Official Symbol: DBR1
Synonyms: DBR1; debranching enzyme homolog 1 (S. cerevisiae); debranching enzyme (S. Cerevisiae) homolog 1; lariat debranching enzyme; RNA lariat debranching enzyme;
Gene ID: 51163
mRNA Refseq: NM_016216
Protein Refseq: NP_057300
MIM: 607024
UniProt ID: Q9UK59
Chromosome Location: 3q22.3
Function: RNA lariat debranching enzyme activity; hydrolase activity, acting on ester bonds; metal ion binding;

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