Recombinant Human DDX1, His-tagged


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Recombinant Human DDX1, His-tagged

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Cat.No. : DDX1-11888H
Product Overview : Recombinant Human DDX1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin.
Source : E.coli
Species : Human
Tag : His
Protein length : C-term-350a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 [ Homo sapiens ]
Official Symbol : DDX1
Synonyms : DDX1; DEAD (Asp-Glu-Ala-Asp) box helicase 1; DEAD (Asp Glu Ala Asp) box polypeptide 1 , DEAD/H (Asp Glu Ala Asp/His) box polypeptide 1; ATP-dependent RNA helicase DDX1; DBP RB; DEAD box-1; DEAD box protein 1; DEAD box polypeptide 1; DEAD box protein retinoblastoma; DEAD (Asp-Glu-Ala-Asp) box polypeptide 1; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1; DBP-RB; UKVH5d;
Gene ID : 1653
mRNA Refseq : NM_004939
Protein Refseq : NP_004930
MIM : 601257
UniProt ID : Q92499
Chromosome Location : 2p24
Pathway : mRNA processing, organism-specific biosystem;
Function : ATP binding; ATP-dependent helicase activity; DNA binding; DNA/RNA helicase activity; RNA binding; RNA helicase activity; chromatin binding; exonuclease activity; hydrolase activity; nuclease activity; nucleotide binding; poly(A) RNA binding; protein bind
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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