Recombinant Human DDX1, His-tagged

• Cat.No.: DDX1-11888H
• Product Overview: Recombinant Human DDX1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: C-term-350a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 [ Homo sapiens ]
• Official Symbol: DDX1
• Synonyms: DDX1; DEAD (Asp-Glu-Ala-Asp) box helicase 1; DEAD (Asp Glu Ala Asp) box polypeptide 1 , DEAD/H (Asp Glu Ala Asp/His) box polypeptide 1; ATP-dependent RNA helicase DDX1; DBP RB; DEAD box-1; DEAD box protein 1; DEAD box polypeptide 1; DEAD box protein retinoblastoma; DEAD (Asp-Glu-Ala-Asp) box polypeptide 1; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1; DBP-RB; UKVH5d
• Gene ID: 1653
• mRNA Refseq: NM_004939
• Protein Refseq: NP_004930
• MIM: 601257
• UniProt ID: Q92499
• Chromosome Location: 2p24
• Pathway: mRNA processing, organism-specific biosystem
• Function: ATP binding; ATP-dependent helicase activity; DNA binding; DNA/RNA helicase activity; RNA binding; RNA helicase activity; chromatin binding; exonuclease activity; hydrolase activity; nuclease activity; nucleotide binding; poly(A) RNA binding; protein bind