"DLC1" Related Products

Recombinant Human DLC1, His-tagged

Cat.No.: DLC1-12016H
Product Overview: Recombinant Human DLC1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.
Source: E.coli
Species: Human
Tag: His
Protein length: 1179-1528a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: DLC1 deleted in liver cancer 1 [ Homo sapiens ]
Official Symbol: DLC1
Synonyms: DLC1; deleted in liver cancer 1; rho GTPase-activating protein 7; ARHGAP7; DLC 1; HP; p122 RhoGAP; StAR related lipid transfer (START) domain containing 12; STARD12; Rho-GTPase-activating protein 7; deleted in liver cancer 1 protein; START domain-containing protein 12; deleted in liver cancer 1 variant 2; rho-type GTPase-activating protein 7; StAR-related lipid transfer (START) domain containing 12; p122-RhoGAP; FLJ21120;
Gene ID: 10395
mRNA Refseq: NM_001164271
Protein Refseq: NP_001157743
MIM: 604258
UniProt ID: Q96QB1
Chromosome Location: 8p22
Pathway: Regulation of RhoA activity, organism-specific biosystem; Rho GTPase cycle, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by Rho GTPases, organism-specific biosystem;
Function: GTPase activator activity; NOT Rac GTPase activator activity; Rho GTPase activator activity; Rho GTPase activator activity; SH2 domain binding; phospholipase binding; protein binding; vinculin binding;
Products Types ◆ Recombinant Protein

◆ Lysates

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