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Recombinant Human DNALI1, GST-tagged

Cat.No.: DNALI1-12093H
Product Overview: Recombinant Human DNALI1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
Source: E.coli
Species: Human
Tag: GST
Protein length: 1-258a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: DNALI1 dynein, axonemal, light intermediate chain 1 [ Homo sapiens ]
Official Symbol: DNALI1
Synonyms: DNALI1; dynein, axonemal, light intermediate chain 1; dynein, axonemal, light intermediate polypeptide 1; axonemal dynein light intermediate polypeptide 1; dJ423B22.5; dJ423B22.5 (axonemal dynein light chain (hp28)); hp28; inner dynein arm; homolog of clamydomonas; P28; inner dynein arm light chain, axonemal; inner dynein arm, homolog of clamydomonas;
Gene ID: 7802
mRNA Refseq: NM_003462
Protein Refseq: NP_003453
MIM: 602135
UniProt ID: O14645
Chromosome Location: 1p35.1
Pathway: Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem;
Function: microtubule motor activity;

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