Recombinant Human DNALI1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: DNALI1-2163H
• Product Overview: DNALI1 MS Standard C13 and N15-labeled recombinant protein (NP_003453) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 31.7 kDa
• AA Sequence: MVTANKAHTGQGSCWVATLASAMIP PADSLLKYDTPVLVSRNTEKRSPKA RLLKVSPQQPGPSGSAPQPPKTKLP STPCVPDPTKQAEEILNAILPPREW VEDTQLWIQQVSSTPSTRMDVVHLQ EQLDLKLQQRQARETGICPVRRELY SQCFDELIREVTINCAERGLLLLRV RDEIRMTIAAYQTLYESSVAFGMRK ALQAEQGKSDMERKIAELETEKRDL ERQVNEQKAKCEATEKRESERRQVE EKKHNEEIQFLKRTNQQLKAQLEGI IAPKKTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DNALI1 dynein axonemal light intermediate chain 1 [ Homo sapiens (human) ]
• Official Symbol: DNALI1
• Synonyms: DNALI1; dynein, axonemal, light intermediate chain 1; dynein, axonemal, light intermediate polypeptide 1; axonemal dynein light intermediate polypeptide 1; dJ423B22.5; dJ423B22.5 (axonemal dynein light chain (hp28)); hp28; inner dynein arm; homolog of clamydomonas; P28; inner dynein arm light chain, axonemal; inner dynein arm, homolog of clamydomonas
• Gene ID: 7802
• mRNA Refseq: NM_003462
• Protein Refseq: NP_003453
• MIM: 602135
• UniProt ID: O14645