Recombinant Human DNMT2, His-tagged
| Cat.No. : | DNMT2-12109H |
| Product Overview : | Recombinant Human DNMT2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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- Gene Information
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| Description : | This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. |
| Source : | E.coli |
| Species : | Human |
| Tag : | His |
| Protein length : | 1-391a.a. |
| Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
| Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
| Gene Name : | TRDMT1 tRNA aspartic acid methyltransferase 1 [ Homo sapiens ] |
| Official Symbol : | TRDMT1 |
| Synonyms : | TRDMT1; tRNA aspartic acid methyltransferase 1; DNA (cytosine 5 ) methyltransferase 2 , DNMT2; tRNA (cytosine(38)-C(5))-methyltransferase; RNMT1; DNA methyltransferase-2; DNA MTase homolog HsaIIP; tRNA (cytosine-5-)-methyltransferase; DNA (cytosine-5)-methyltransferase-like protein 2; DMNT2; DNMT2; PUMET; MHSAIIP; |
| Gene ID : | 1787 |
| mRNA Refseq : | NM_004412 |
| Protein Refseq : | NP_004403 |
| MIM : | 602478 |
| UniProt ID : | O14717 |
| Chromosome Location : | 10p15.1 |
| Function : | DNA (cytosine-5-)-methyltransferase activity; DNA binding; RNA binding; methyltransferase activity; transferase activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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