"DOHH" Related Products


Recombinant Human DOHH, His-tagged

Cat.No.: DOHH-12125H
Product Overview: Recombinant Human DOHH protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: This gene encodes a metalloenzyme that catalyzes the last step in the conversion of lysine to the unique amino acid hypusine in eukaryotic initiation factor 5A. The encoded protein hydroxylates deoxyhypusine to form hypusine in the mature eukaryotic initiation factor 5A protein. Alternative splicing results in multiple transcript variants.
Source: E.coli
Species: Human
Tag: His
Protein length: 1-302a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: DOHH deoxyhypusine hydroxylase/monooxygenase [ Homo sapiens ]
Official Symbol: DOHH
Synonyms: DOHH; deoxyhypusine hydroxylase/monooxygenase; HEAT like (PBS lyase) repeat containing 1 , HLRC1; deoxyhypusine hydroxylase; MGC4293; deoxyhypusine dioxygenase; deoxyhypusine monooxygenase; HEAT-like repeat-containing protein 1; HEAT-like (PBS lyase) repeat containing 1; HLRC1; hDOHH;
Gene ID: 83475
mRNA Refseq: NM_001145165
Protein Refseq: NP_001138637
MIM: 611262
UniProt ID: Q9BU89
Chromosome Location: 19p13.3
Pathway: Hypusine synthesis from eIF5A-lysine, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, organism-specific biosystem; Post-translational protein modification, organism-specific biosystem; hypusine biosynthesis, organism-specific biosystem; hypusine biosynthesis, conserved biosystem;
Function: deoxyhypusine monooxygenase activity; deoxyhypusine monooxygenase activity; metal ion binding; protein binding;

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