"EXOSC8" Related Products

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Recombinant Human EXOSC8, His-tagged

Cat.No.: EXOSC8-12600H
Product Overview: Recombinant Human EXOSC8 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: This gene encodes a 3-5 exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.
Source: E.coli
Species: Human
Tag: His
Protein length: 1-276a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: EXOSC8 exosome component 8 [ Homo sapiens ]
Official Symbol: EXOSC8
Synonyms: EXOSC8; exosome component 8; exosome complex component RRP43; bA421P11.3; CBP interacting protein 3; CIP3; EAP2; OIP2; Opa interacting protein 2; p9; RRP43; Rrp43p; OIP-2; CBP-interacting protein 3; opa-interacting protein 2; exosome complex exonuclease RRP43; ribosomal RNA-processing protein 43; RP11-421P11.3;
Gene ID: 11340
mRNA Refseq: NM_181503
Protein Refseq: NP_852480
MIM: 606019
UniProt ID: Q96B26
Chromosome Location: 13q13.1
Pathway: Activation of Genes by ATF4, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by KSRP, organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem;
Function: AU-rich element binding; RNA binding; NOT exoribonuclease activity; protein binding;

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