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Recombinant Human EXOSC8, His-tagged

Cat.No. : EXOSC8-12600H
Product Overview : Recombinant Human EXOSC8 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
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Description : This gene encodes a 3-5 exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.
Source : E.coli
Species : Human
Tag : His
Protein length : 1-276a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : EXOSC8 exosome component 8 [ Homo sapiens ]
Official Symbol : EXOSC8
Synonyms : EXOSC8; exosome component 8; exosome complex component RRP43; bA421P11.3; CBP interacting protein 3; CIP3; EAP2; OIP2; Opa interacting protein 2; p9; RRP43; Rrp43p; OIP-2; CBP-interacting protein 3; opa-interacting protein 2; exosome complex exonuclease RRP43; ribosomal RNA-processing protein 43; RP11-421P11.3;
Gene ID : 11340
mRNA Refseq : NM_181503
Protein Refseq : NP_852480
MIM : 606019
UniProt ID : Q96B26
Chromosome Location : 13q13.1
Pathway : Activation of Genes by ATF4, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by KSRP, organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem;
Function : AU-rich element binding; RNA binding; NOT exoribonuclease activity; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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