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Recombinant Human FARS2, GST-tagged

Cat.No. : FARS2-12748H
Product Overview : Recombinant Human FARS2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
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Description : Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. This gene encodes a phenylalanine-tRNA synthetase (PheRS) localized to the mitochondrion which consists of a single polypeptide chain, unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and in the eukaryotic cytoplasm.
Source : E.coli
Species : Human
Tag : GST
Protein length : 109-451a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial [ Homo sapiens ]
Official Symbol : FARS2
Synonyms : FARS2; phenylalanyl-tRNA synthetase 2, mitochondrial; FARS1, phenylalanine tRNA synthetase 1 (mitochondrial); phenylalanine--tRNA ligase, mitochondrial; dJ236A3.1; phenylalanine tRNA ligase 2; mitochondrial; phenylalanine translase; dJ236A3.1 (phenylalanine-tRNA synthetase); phenylalanine tRNA ligase 2, mitochondrial; phenylalanyl-tRNA synthetase, mitochondrial; phenylalanine-tRNA synthetase 1 (mitochondrial); phenylalanine-tRNA synthetase 2 (mitochondrial); dJ520B18.2 (FARS1 (phenylalanine-tRNA synthetase)); FARS1; PheRS; HSPC320; dJ520B18.2;
Gene ID : 10667
mRNA Refseq : NM_006567
Protein Refseq : NP_006558
MIM : 611592
UniProt ID : O95363
Chromosome Location : 6p25.1
Pathway : Aminoacyl-tRNA biosynthesis, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conserved biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; Gene Expression, organism-specific biosystem; Mitochondrial tRNA aminoacylation, organism-specific biosystem; tRNA Aminoacylation, organism-specific biosystem;
Function : ATP binding; aminoacyl-tRNA ligase activity; ligase activity; magnesium ion binding; nucleotide binding; phenylalanine-tRNA ligase activity; tRNA binding; tRNA binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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