Recombinant Human FCGR2C, GST-tagged

• Cat.No.: FCGR2C-12821H
• Product Overview: Recombinant Human FCGR2C protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-70a.a.
• Description: This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) [ Homo sapiens ]
• Official Symbol: FCGR2C
• Synonyms: Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene); 15626; low affinity immunoglobulin gamma Fc region receptor II-c;fc-gamma-RIIc;IgG Fc receptor II-c;Fc gamma receptor IIC;immunoglobulin G Fc receptor II-c; CD32; FCG2; CD32C; CDW32; IGFR2; FCRIIC
• Gene ID: 9103
• mRNA Refseq: NM_201563.4
• Protein Refseq: NP_963857.3
• MIM: 612169
• Chromosome Location: 1q23.3
• Pathway: Adaptive Immune System, organism-specific biosystem; Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Leishmaniasis, organism-specific biosystem; Leishmaniasis, conserved biosystem
• Function: IgG binding; protein binding; transmembrane signaling receptor activity