Recombinant Human FMR1, GST-tagged FMR1-12948H

Recombinant Human FMR1, GST-tagged

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Recombinant Human FMR1, GST-tagged

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Cat.No. : FMR1-12948H
Product Overview : Recombinant Human FMR1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5 UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-297a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : FMR1 fragile X mental retardation 1 [ Homo sapiens ]
Official Symbol : FMR1
Synonyms : FMR1; fragile X mental retardation 1; POF, POF1, premature ovarian failure 1; fragile X mental retardation protein 1; FMRP; FRAXA; MGC87458; protein FMR-1; fragile X mental retardation 1 protein; POF; POF1;
Gene ID : 2332
mRNA Refseq : NM_001185075
Protein Refseq : NP_001172004
MIM : 309550
UniProt ID : Q06787
Chromosome Location : Xq27.3
Pathway : RNA transport, organism-specific biosystem; RNA transport, conserved biosystem;
Function : RNA binding; RNA binding; mRNA binding; protein binding;

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