Recombinant Human FOSB, GST-tagged

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Recombinant Human FOSB, GST-tagged

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Cat.No. : FOSB-12964H
Product Overview : Recombinant Human FOSB protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source : E.coli
Species : Human
Tag : GST
Protein length : 2-14a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : FOSB FBJ murine osteosarcoma viral oncogene homolog B [ Homo sapiens ]
Official Symbol : FOSB
Synonyms : FOSB; FBJ murine osteosarcoma viral oncogene homolog B; protein fosB; activator protein 1; AP 1; DKFZp686C0818; GOS3; GOSB; G0S3; MGC42291; oncogene FOS B; G0/G1 switch regulatory protein 3; AP-1;
Gene ID : 2354
mRNA Refseq : NM_001114171
Protein Refseq : NP_001107643
MIM : 164772
UniProt ID : P53539
Chromosome Location : 19q13.3
Pathway : Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Cocaine addiction, organism-specific biosystem; Cocaine addiction, conserved biosystem; Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem;
Function : DNA binding; protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor binding;

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