Recombinant Human GHR protein

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Human GHR protein

Recombinant Human GHR protein

GHR Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : GHR-39H
Product Overview : Recombinant Human GHR was expressed in E. coli.
Description : GHBP is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized.
Source : E. coli
Species : Human
Form : GHBP was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3.
Molecular Mass : 28107.01 Dalton
AA Sequence : AFSGSEATAA ILSRAPWSLQ SVNPGLKTNS SKEPKFTKCR SPERETFSCH WTDEVHHGTK NLGPIQLFYT RRNTQEWTQE WKECPDYVSA GENSCYFNSS FTSIWIPYCI KLTSNGGTVD <br/>EKCFS VDEIVQPDPP IALNWTLLNV SLTGIHADIQ VRWEAPRNAD IQKGWMVLEY ELQYKEVNET KWKMMDPILT TSVPVYSLKV DKEYEVRVRS KQRNSGNYGE FSEVLYVTLP QMSQF<br/> TCEEDFYF.
Purity : Greater than 98.0% as determined by:
(a) Analysis by SEC-HPLC.
(b) Analysis by SDS-PAGE.
Storage : Lyophilized Growth Hormone Binding Protein although stable at room temperature for 3 weeks, should be stored desiccated below -18 centigrade. Upon reconstitution GHBP should be stored at 4 centigrade between 2-7 days and for future use below -18 centigrade.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Reconstitution : It is recommended to reconstitute the lyophilized Growth Hormone Binding Protein in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Gene Name : GHR growth hormone receptor [ Homo sapiens ]
Official Symbol : GHR
Synonyms : GHR; growth hormone receptor; GH receptor; serum binding protein; somatotropin receptor; growth hormone binding protein; GHBP;
Gene ID : 2690
mRNA Refseq : NM_000163
Protein Refseq : NP_000154
MIM : 600946
UniProt ID : P10912
Chromosome Location : 5p14-p12
Pathway : Androgen Receptor Signaling Pathway, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Endochondral Ossification, organism-specific biosystem; Growth hormone receptor signaling, organism-specific biosystem; Immune System, organism-specific biosystem;
Function : SH2 domain binding; growth factor binding; growth hormone receptor activity; peptide hormone binding; proline-rich region binding; protein binding; protein homodimerization activity; protein kinase binding; protein phosphatase binding; receptor activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Online Inquiry


  • Note: There will be extra charge for optional service!

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy