"GABRA6" Related Products


Recombinant Human GABRA6, His-tagged

Cat.No.: GABRA6-13096H
Product Overview: Recombinant Human GABRA6 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
Source: E.coli
Species: Human
Tag: His
Protein length: 329-424a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 [ Homo sapiens ]
Official Symbol: GABRA6
Synonyms: GABRA6; gamma-aminobutyric acid (GABA) A receptor, alpha 6; gamma-aminobutyric acid receptor subunit alpha-6; GABA(A) receptor; alpha 6; GABA(A) receptor, alpha 6; GABA subunit A receptor alpha 6; GABA(A) receptor subunit alpha-6; MGC116903; MGC116904;
Gene ID: 2559
mRNA Refseq: NM_000811
Protein Refseq: NP_000802
MIM: 137143
UniProt ID: Q16445
Chromosome Location: 5q34
Pathway: GABA A receptor activation, organism-specific biosystem; GABA receptor activation, organism-specific biosystem; GABAergic synapse, organism-specific biosystem; GABAergic synapse, conserved biosystem; Ion channel transport, organism-specific biosystem; Ligand-gated ion channel transport, organism-specific biosystem; Morphine addiction, organism-specific biosystem;
Function: GABA-A receptor activity; GABA-gated chloride ion channel activity; benzodiazepine receptor activity; chloride channel activity; drug binding; inhibitory extracellular ligand-gated ion channel activity; ion channel activity; receptor activity;

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