Recombinant Human GGPS1, GST-tagged

• Cat.No.: GGPS1-13243H
• Product Overview: Recombinant Human GGPS1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Guanylate-binding proteins, such as GBP6, are induced by interferon and hydrolyze GTP to both GDP and GMP (Olszewski et al., 2006 [PubMed 16689661]).
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-300a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GGPS1 geranylgeranyl diphosphate synthase 1 [ Homo sapiens ]
• Official Symbol: GGPS1
• Synonyms: GGPS1; geranylgeranyl diphosphate synthase 1; geranylgeranyl pyrophosphate synthase; GGPPS1; GGPPSase; GGPP synthase; geranyltranstransferase; farnesyltranstransferase; dimethylallyltranstransferase; farnesyl diphosphate synthase; (2E,6E)-farnesyl diphosphate synthase; GGPPS
• Gene ID: 9453
• mRNA Refseq: NM_001037277
• Protein Refseq: NP_001032354
• MIM: 606982
• UniProt ID: O95749
• Chromosome Location: 1q43
• Pathway: Cholesterol biosynthesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Terpenoid backbone biosynthesis, organism-specific biosystem; Terpenoid backbone biosynthesis, conserved biosystem; geranylgeranyldiphosphate biosynthesis, organism-specific biosystem
• Function: dimethylallyltranstransferase activity; farnesyltranstransferase activity; geranyltranstransferase activity; metal ion binding; transferase activity