Recombinant Human GNA11, His-tagged

• Cat.No.: GNA11-13342H
• Product Overview: Recombinant Human GNA11 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-170a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) [ Homo sapiens ]
• Official Symbol: GNA11
• Synonyms: guanine nucleotide binding protein (G protein), alpha 11 (Gq class); 4379; Ensembl:ENSG00000088256; guanine nucleotide-binding protein subunit alpha-11;g alpha-11;G-protein subunit alpha-11;guanine nucleotide-binding protein, Gq class, GNA11;guanine nucleotide-binding protein G(y) subunit alpha; GNA-11
• Gene ID: 2767
• mRNA Refseq: NM_002067.2
• Protein Refseq: NP_002058.2
• MIM: 139313
• UniProt ID: P29992
• Chromosome Location: 19p13.3
• Pathway: ADP signalling through P2Y purinoceptor 1, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Arf6 signaling events, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem
• Function: G-protein beta/gamma-subunit complex binding; G-protein coupled receptor binding; GTP binding; GTPase activity; metal ion binding; signal transducer activity