Recombinant Human GNB1L, His-tagged

• Cat.No.: GNB1L-13354H
• Product Overview: Recombinant Human GNB1L protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-327a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like [ Homo sapiens ]
• Official Symbol: GNB1L
• Synonyms: guanine nucleotide binding protein (G protein), beta polypeptide 1-like; 4397; Ensembl:ENSG00000185838; KIAA1645; guanine nucleotide-binding protein subunit beta-like protein 1;WD repeat-containing protein 14;G-protein beta subunit-like protein;g protein subunit beta-like protein 1;WD40 repeat-containing protein deleted in VCFS;guanine nucleotide binding protein beta-subunit-like polypeptide; GY2; FKSG1; WDR14; WDVCF; DGCRK3
• Gene ID: 54584
• mRNA Refseq: NM_053004.2
• Protein Refseq: NP_443730.1
• MIM: 610778
• UniProt ID: Q9BYB4
• Chromosome Location: 22q11.2
• Function: molecular_function