Recombinant Human GPR176, His-tagged

• Cat.No.: GPR176-13464H
• Product Overview: Recombinant Human GPR176 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 325-514a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: GPR176 G protein-coupled receptor 176 [ Homo sapiens ]
• Official Symbol: GPR176
• Synonyms: agr9; G protein coupled receptor 176; Gm1012; GP176_HUMAN; GPR; Gpr176; HB 954; HB-954; HB954; Probable G-protein coupled receptor 176; Putative G protein coupled receptor
• Gene ID: 11245
• mRNA Refseq: NM_001271854.1
• Protein Refseq: NP_009154.1
• MIM: 612183
• UniProt ID: Q14439
• Chromosome Location: 15q14-q15.1
• Pathway: GPCRs,Other,organism-specific biosystem
• Function: G-protein coupled receptor activity