"HES6" Related Products


Recombinant Human HES6, His-tagged

Cat.No.: HES6-13748H
Product Overview: Recombinant Human HES6 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: This gene encodes a member of a subfamily of basic helix-loop-helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of this gene family regulate cell differentiation in numerous cell types. The protein encoded by this gene functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C-terminus. Alternatively spliced transcript variants encoding different isoforms have been described.
Source: E.coli
Species: Human
Tag: His
Protein length: 1-224a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: HES6 hairy and enhancer of split 6 (Drosophila) [ Homo sapiens ]
Official Symbol: HES6
Synonyms: HES6; hairy and enhancer of split 6 (Drosophila); transcription cofactor HES-6; bHLHb41; C-HAIRY1; class B basic helix-loop-helix protein 41; HES-6; bHLHc23;
Gene ID: 55502
mRNA Refseq: NM_001142853
Protein Refseq: NP_001136325
MIM: 610331
UniProt ID: Q96HZ4
Chromosome Location: 2q37.3
Pathway: Delta-Notch Signaling Pathway, organism-specific biosystem; Notch-mediated HES/HEY network, organism-specific biosystem;
Function: DNA binding; sequence-specific DNA binding transcription factor activity; transcription cofactor activity; transcription factor binding;

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